CD6 Antibody Cocktail orb248235 from Biorbyt

Description

CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular “scavenger receptor cysteine-rich” (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. antibody to CD6 can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease

Product Specs
ItemCD6 Antibody Cocktail
CompanyBiorbyt
Price Pricing Info Supplier Page
Catalog Numberorb248235
Quantity20 µg, 100 µg
ApplicationsIF, IHC-P
Conjugate/TagUnconjugated
PurityProtein G Affinity Chromatography
ReactivityHuman
TargetCD6
IsotypeMouse IgG1, kappa
CloneC6/372 + 3F7B5
HostMouse
ImmunogenHuman recombinant CD6 protein (C6/372) and the rheumatoid synovial T cell line ST-1 (3F7B5) were used as the immunogen for this antibody cocktail
NCBI Full Gene NameCD6 molecule
NCBI Gene AliasesTP120
ClonalityMonoclonal
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
StorageStore the CD6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide)

Specifications/Features

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Application Dilutions: Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT

Add to Compare List